[Potential prevention of cervical cancer in Chile by the papilloma virus vaccine (HPV): More questions than answers].
نویسنده
چکیده
se ha ido desplazando hacia arriba el punto de corte para hablar de déficit de vitamina D. Como bien dice, aplicando este nuevo punto de corte a la muestra en comento, 42,5% estaría en situación deficitaria. El año 2007 publicamos un nuevo trabajo2 en el cual medimos la 25-hidroxivitamina D en otra muestra de más de 500 mujeres de similares características a las anteriores. En ellas relacionamos los niveles de 25-hidroxivitamina D con los niveles de PTH mediante una curva ROC, con lo cual encontramos que, a niveles de 17 ng/mL de calcidiol, empezaba a subir la PTH. En ese estudio 47,5% de la muestra tenía concentraciones plasmáticas de 25-hidroxivitamina D por debajo de ese punto de corte. En 2003, González et al (observaciones no publicadas) encontraron 38% de pacientes deficitarias de vitamina D con hiperparatiroidismo secundario en una muestra de 79 mujeres adultas mayores, dentro de un universo de 82% de hipovitaminosis D. Subsiste la pregunta sobre las consecuencias que pueda tener este déficit universal de vitamina D, en particular en los tramos más leves (20-30 ng/mL). Hay abundante literatura que muestra asociaciones estadísticas entre el déficit y las más variadas condiciones, como las que enumera el Dr. Lama, y diversos metaanálisis muestran que la suplementación con vitamina D reduce significativa aunque levemente la mortalidad por cualquier causa3.
منابع مشابه
Knowledge and Attitudes of Medical Students about Human Papilloma Virus (HPV) Vaccination and Associated Factors
Introduction: The prevalence of human papilloma virus (HPV) is growing in the world. According to the precancerous role and the importance of prevention, human papilloma virus vaccination is considered in all countries. The knowledge and attitude of patients have a considerable effect on HPV injection. It seems that higher knowledge level of physicians can have significant effect on justificati...
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Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...
متن کاملCost-Effectiveness Evaluation of Quadrivalent Human Papilloma Virus Vaccine for HPV-Related Disease in Iran
Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...
متن کاملبررسی وفور عفونت ویروس پاپیلومای انسانی HPV در ضایعات بدخیم دهانه رحم به روش PCR مولتی پلکس
Background: Cervical cancer is the second leading cause of cancer death among women. In this cancer, the effects of prevention, early diagnosis and treatment more than other cancers decrease the mortality rate. In 1970 human papilloma virus (HPV) was introduction as major etiologic factor of cervical cancer. Different studies throughout the world revealed strong correlation between HPV and canc...
متن کاملPrevalence Of Human Papilloma Virus Among Women With Cervical Intraepithelial Neoplasia III And Invasive Cervical Cancer From 2001 To 2006 In Bandarabas
Background and Objective: To estimate the risk of human papilloma virus (HPV) infection for cervical malignancies, we conducted a case-control study in southern Iran (Hormozgan province). Materials and Methods: For this purpose,52 paraffin embedded blocks with exact diagnosis of cervical carcinoma(50 carcinomas and 2 carcinomas in situ) from 2001 to 2006 and 52 praffin embedded blocks of ce...
متن کاملFailure to Demonstrate the Role of High Risk Human Papilloma Virus in Epithelial Ovarian Cancer
Background and Aims: Ovarian cancer is one of most common causes of cancer related women's mortalities. Human papilloma virus is a known factor concerning cervical cancer but its role in causing ovarian cancer is not yet verified. A few studies also identified HPV DNA in ovarian carcinoma tissues. However, some studies did not detect HPV DNA in ovarian carcinoma tissues. In this articl...
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ورودعنوان ژورنال:
- Revista medica de Chile
دوره 137 7 شماره
صفحات -
تاریخ انتشار 2009